GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations.

TitleGRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations.
Publication TypeJournal Article
Year of Publication2013
AuthorsAndrews J, Guyatt G, Oxman AD, Alderson P, Dahm P, Falck-Ytter Y, Nasser M, Meerpohl J, Post PN, Kunz R, Brozek J, Vist G, Rind D, Akl EA, Sch├╝nemann HJ
JournalJournal of clinical epidemiology
Volume66
Issue7
Pagination719-25
Date Published2013 Jul
ISSN1878-5921
Abstract

This article describes the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to classifying the direction and strength of recommendations. The strength of a recommendation, separated into strong and weak, is defined as the extent to which one can be confident that the desirable effects of an intervention outweigh its undesirable effects. Alternative terms for a weak recommendation include conditional, discretionary, or qualified. The strength of a recommendation has specific implications for patients, the public, clinicians, and policy makers. Occasionally, guideline developers may choose to make "only-in-research" recommendations. Although panels may choose not to make recommendations, this choice leaves those looking for answers from guidelines without the guidance they are seeking. GRADE therefore encourages panels to, wherever possible, offer recommendations.

DOI10.1016/j.jclinepi.2012.03.013
Alternate JournalJ Clin Epidemiol