|Title||Search strategies to identify information on adverse effects: a systematic review.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Golder S, Loke Y|
|Journal||Journal of the Medical Library Association : JMLA|
|Date Published||2009 Apr|
|Keywords||Abstracting and Indexing as Topic; Databases, Factual; Drug Therapy; Drug Toxicity; Guidelines as Topic; Humans; Information Storage and Retrieval; Meta-Analysis as Topic; Periodicals as Topic; Quality Control; Research Design; Review Literature as Topic; Vocabulary, Controlled|
OBJECTIVES: The review evaluated studies of electronic database search strategies designed to retrieve adverse effects data for systematic reviews.
METHODS: Studies of adverse effects were located in ten databases as well as by checking references, hand-searching, searching citations, and contacting experts. Two reviewers screened the retrieved records for potentially relevant papers.
RESULTS: Five thousand three hundred thirteen citations were retrieved, yielding 19 studies designed to develop or evaluate adverse effect filters, of which 3 met the inclusion criteria. All 3 studies identified highly sensitive search strategies capable of retrieving over 95% of relevant records. However, 1 study did not evaluate precision, while the level of precision in the other 2 studies ranged from 0.8% to 2.8%. Methodological issues in these papers included the relatively small number of records, absence of a validation set of records for testing, and limited evaluation of precision.
CONCLUSIONS: The results indicate the difficulty of achieving highly sensitive searches for information on adverse effects with a reasonable level of precision. Researchers who intend to locate studies on adverse effects should allow for the amount of resources and time required to conduct a highly sensitive search.
|Alternate Journal||J Med Libr Assoc|